FOXO-regulated transcription restricts overgrowth of Tsc mutant organs.

J Cell Biol · 2008 · PMC2265581 · PMID 18299344

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highly significantP = 4.9 × 10 e−009actually significant

This analysis revealed that 25 genes were up-regulated 1.5-fold or greater in both Tsc1 LOF and FOXO GOF expression profiles, which represents a highly significant degree of overlap (P = 4.9 × 10 e−009 ) as determined by calculation of the hypergeometric distribution.

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