Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder.

Behav Brain Funct · 2008 · PMC2267477 · PMID 18201382

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

borderline significantp = 0.07so close (0.05 < p ≤ 0.1)

Association between BPAD and CC33 genotype was borderline significant (p = 0.07), with an higher risk to develop bipolar disorder for 'CT' or 'TT' carriers versus 'CC' carriers (OR = 1.8 [1.01–3.0]; p = 0.05) and a significant allelic association was observed with the 'T'-allele of CC33 (p = 0.05, see Table 1 for details).

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highly significantno p-value reported

Finally, 8p21 has also been identified as a highly significant susceptibility locus for a psychotic form of BPAD [ 13 ].

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