The DNA binding capabilities of RAG1 alone may be significant since it is not clear if the V(D)J recombinase binds to the RSS as a pre-formed complex, or if RAG1 binds first, followed by RAG2.
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The DNA binding capabilities of RAG1 alone may be significant since it is not clear if the V(D)J recombinase binds to the RSS as a pre-formed complex, or if RAG1 binds first, followed by RAG2.