highly significantp < 0.001
The difference between the individual temperature groups at low and high concentrations is therefore small. From an ANOVA analysis, we found that the effect of doxorubicin concentration on NHEK viability was highly significant [ F (6,161) = 165.213, p < 0.001], as was the effect of temperature on NHEK viability [ F (6,161) = 37.054, p < 0.001].