Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor.

J Mol Signal · 2008 · PMC2278143 · PMID 18355401

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may be significantno p-value reported

Since Ras is an upstream target of ERK, the inhibition of Ras/Raf/MEK/ERK pathway by EGCG may be significant to inhibit angiogenesis.

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