Barely Significant
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Therapeutic Potential of PPARγ Activation in Stroke.

PPAR Res · 2008 · PMC2293414 · PMID 21909480

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an encouraging trendno p-value reported
While this shows an encouraging trend for stroke patients, serious heart failure was observed to be increased significantly in the pioglitazone group compared to placebo group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.