Other highly significant clusters were found in the 4D1 area, surrounding the Ppt1 locus, ranging from Ptprf to NADH dehydrogenase (ubiquinone) Fe-S protein 5 (Ndufs5) (nominal p = -8.1 × 10 -6 ; permuted p = 1.9 × 10 -4 ).
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Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases.
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