highly significantP =0.00006
The combined data ( Tables 7 and 8 ) reveal a highly significant association ( P =0.00006) with an OR of 3.06 (95% CI: 1.74–5.3) for patients carrying at least one variant allele (CT or TT) compared with the homozygous wild-type CC genotype, and therefore this increased risk applies to ∼56% (132/236) of breast cancer patients.