An individual patient data meta-analysis of adjuvant therapy with uracil-tegafur (UFT) in patients with curatively resected rectal cancer.

Br J Cancer · 2007 · PMC2360162 · PMID 17375049

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highly significantno p-value reported

The results of the random effect model still revealed highly significant differences owing to the relatively high effect in TAC–CR and NSAS-CC trials.

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a slight trendno p-value reported

There was a slight trend toward larger treatment benefits in earlier Dukes' stages (Hazard ratio; Dukes' A =0.60, Dukes' B =0.79, Dukes' C =0.86) but heterogeneity tests did not show any significant difference ( χ 2 2 =1.41; P =0.495).

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