Barely Significant
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Intensive follow-up after liver resection for colorectal liver metastases: results of combined serial tumour marker estimations and computed tomography of the chest and abdomen - a prospective study.

Br J Cancer · 2006 · PMC2360492 · PMID 16804525

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may be significantno p-value reported
Even if early detection does not allow potentially curative resection of recurrent liver metastases, there may be significant clinical benefit to the earlier commencement of systemic chemotherapy or the use of radiofrequency ablation ( Elias et al , 2004 ; Gillams and Lees, 2005 ).

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