The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens.

Br J Cancer · 2006 · PMC2360579 · PMID 17024127

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The sentences

highly significantno p-value reported

In tumours, where numbers of T REG may be greatly increased, this immunosuppressive effect may be highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.