highly significantP <0.0001
Estramustine phosphate did not produce significant increases in CK18-Asp396 ( P =0.13), whereas highly significant increases in total CK18 were observed ( P <0.0001).
Estramustine phosphate did not produce significant increases in CK18-Asp396 ( P =0.13), whereas highly significant increases in total CK18 were observed ( P <0.0001).
Vinorelbine induced significant increase in CK18-Asp396 during second-line therapy ( P <0.005), whereas the increases during third line were of borderline significance ( P =0.048).