highly significantP <0.001
There was also a highly significant association between a high Cyclin A score and OS from diagnosis ( Figure 1 ), RR 1.05 (95% CI 1.02–1.07), P <0.001 (as continuous variable) and RR 2.49 (95% CI 1.45–4.29), P =0.004 (as discrete variable), but not for survival from start of first- or second-line chemotherapy.