Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability.

Tumours showing high levels of expression showed a highly significant excess of allelic imbalance (67 loci imbalanced vs 54 balanced) over those with low-level (42 imbalanced vs 81 balanced) expression ( P =0.0012).

also in 132,142 other papers