A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil.

Br J Cancer · 1999 · PMC2362780 · PMID 10206306

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

at the limit of significanceP = 0.058so close (0.05 < p ≤ 0.1)

Regarding p53 protein, median values were higher in non-complete responding patients, although this observa- tion was at the limit of significance in the RChem group only (1.033 ng mg-1 in PR + failure patients vs 0.086 ng mg-1 in CR patients, P = 0.058).

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