Determination of c-myc amplification and overexpression in breast cancer patients: evaluation of its prognostic value against c-erbB-2, cathepsin-D and clinicopathological characteristics using univariate and multivariate analysis.

Br J Cancer · 1999 · PMC2362965 · PMID 10604737

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0.0016

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0.0016

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highly significantP = 0.0016actually significant

Using univariate analysis we proved that c-myc amplification and overexpression were highly significant for disease-free survival (DFS) ( P = 0.0016 and P = 0.0001 respectively) and overall survival (OS) ( P < 0.0001 and P = 0.0095 respectively), although by multivariate analysis c-myc overexpression was statistically significant only for DFS ( P = 0.0001) and c-myc amplification only for OS ( P = 0.0006).

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