Following these guidelines, the 328 patients of the study were divided into four groups: * Group I: patients who had radical metastasectomy and no adverse prognostic factors (TPM > 36 months and single metastasis, n = 96) * Group II: radical metastasectomy and one unfavourable factor (TPM < 36 months or multiple metastases, n = 126) * Group III: radical metastasectomy and two unfavourable factors (TPM < 36 months and multiple metastases, n = 52) * Group IV: incomplete metastasectomy (n = 46). The survival difference among these groups was highly significant (log-rank 2 29.6, df 3, Figure 2).
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