highly significantP = 0.0002
Cytotoxic effects of 5′DFUR, and to a lesser extent those of 5FU, were enhanced in TP clones as compared to control cells: there was a highly significant correlation between TP activity and in vitro sensitivity to 5’DFUR (r 2 = 0.91, P = 0.0002, n = 8) and, to a lesser extent, to 5FU (r 2 = 0.49, P = 0.053, n = 8).