highly significantp < 0.001
Addition of similar dose of PTX during LAK cells assay, however, was not effective (result not shown). Effects of PTX on cytokine production and their receptor expression: PBMC activated with LPS for 48 to 72 h with or without PTX when analysed for the surface receptor expression of IL-I, IL-2, TNF- and the cytokine production of IL-1, IL-2, TNF-, IL-6 and IFN-2 in the supernatant of these cultures indicated (Figs 4 and 5) a highly significant (p < 0.001) suppression of cytokine production and their surface receptor expression in the presence of ( < 0.05) PTX.