Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis.

J Exp Med · 2008 · PMC2373846 · PMID 18458111

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a nonsignificant trendno p-value reported

5 ), whereas osteoclast numbers show a nonsignificant trend to increase ( Table II ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.