pAkt and other variables in relation to distant recurrence-free survival In univariate analysis neither HRG nor Akt-1 had prognostic value, while pAkt positivity predicted a higher risk of developing metastasis with borderline significance (RR=2.4, 95% CI, 1.0–6.2) (see Figure 2A ).
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Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients.
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