Irinotecan plus leucovorin-modulated 5-fluorouracil I.V. bolus every other week may be a suitable therapeutic option also for elderly patients with metastatic colorectal carcinoma.

Br J Cancer · 2003 · PMC2376956 · PMID 12966414

Europe PMC DOI

hedged sentence

0.0990

closest p · 2.0× alpha

0.0990

boldest claim

The sentences

of borderline significanceP =0.099so close (0.05 < p ≤ 0.1)

In the multivariate analysis, taking into account all pretreatment characteristics, the presence of disease-related symptoms was the only variable significantly associated with a shorter PFS ( P =0.053), while age group was of borderline significance ( P =0.099).

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