Tumor necrosis factor alpha drugs in rheumatoid arthritis: systematic review and metaanalysis of efficacy and safety.

BMC Musculoskelet Disord · 2008 · PMC2377247 · PMID 18419803

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marginally significantno p-value reported

The heterogeneity was marginally significant for ACR20 and significant for ACR50 (Table 4 ).

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marginally statistically significantno p-value reported

When the effect of an anti-TNFα drug is assessed in patients who have received no previous MTX treatment, the relative ACR20 effect is small and only marginally statistically significant: 1.10 (0.96–1.26).

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