Analysis of EBV-positive and -negative subgroups by Edwards' method revealed a highly significant peak onset of symptoms for EBV-positive patients occurring at the end of July/early August ( θ =31°+180°=211°) with a trough at the beginning of February ( θ =31°) ( P =0.0093; Figure 1 ).
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Seasonal differences in the onset of the EBV-positive and -negative forms of paediatric Hodgkin's lymphoma.
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