Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells.

Linear regression analysis revealed that the relationship between dose and tail moment was linear, over the 0–5 Gy dose range tested, for each of the cell lines, although the amount of DNA damage per unit dose ( Table 1 ) varied by two-fold between the most radioresistant (HT29) and the most radiosensitive (SW48) cell lines; this difference was highly significant ( P <0.0001).

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