Barely Significant
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Sequence features of HLA-DRB1 locus define putative basis for gene conversion and point mutations.

BMC Genomics · 2008 · PMC2408603 · PMID 18489735

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highly significantno p-value reported
However, the highly significant pattern of conserved CpG in HLA-DRB1-e2 can be considered unlikely even if the CpG dinucleotides were unmethylated and mutated at the rate of other bases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.