Characterisation of molecular events following cisplatin treatment of two curable ovarian cancer models: contrasting role for p53 induction and apoptosis in vivo.

Increased expression of BAX and BAK may be significant as the products of these genes have been reported to be involved in the induction of apoptosis following treatment with anticancer agents ( Jones et al , 1998 ; Ionov et al , 2000 ; Zhang et al , 2000 ). cDNA microarray analysis of cell cycle and apoptosis gene expression following CDDP treatment G

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