Association of NQO1 polymorphism with spontaneous breast cancer in two independent populations.

Br J Cancer · 2004 · PMC2410282 · PMID 15138483

Europe PMC DOI

hedged sentences

0.0004

closest p · 0.0× alpha

0.0440

boldest claim

The sentences

highly significantP =0.0004actually significant

Combining the results of the two populations, we observed a highly significant difference ( P =0.0004) of genotype and allele frequencies (odds ratio (OR)=1.46; 95% confidence interval (CI) 1.16–1.85; P =0.001) and of the homozygote ratio (OR=3.8; 95% CI 1.73–8.34; P =0.0001).

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borderline significantP =0.044actually significant

In addition, also the R72P SNP in the TP53 gene showed a borderline significant difference regarding allele frequencies (OR=1.27; 95% CI 1.00–1.61; P =0.044) and the homozygote ratio (OR=1.77; 95% CI 1.00–3.13; P =0.04).

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