The exact mechanism behind this relationship is ambiguous, however it may be significant that the expression of Pax7 precedes that of Pax3 within the headfold and primitive fold ectoderm in the developing chick [ 2 ].
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Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development.
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