An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load.

PLoS One · 2008 · PMC2440801 · PMID 18596917

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0520

boldest claim

The sentences

highly significantP<0.001actually significant

The FT-AT AUROCs predictive values for survival without HBV complications were still highly significant after exclusion of 16 patients with FT high-risk profiles of false positives/negatives (n = 1,058 AUROC = 0.88, 95%CI 0.81–0.92; P<0.001), Impact of HBV treatment on biomarkers Among the treated patients, the first FT has been performed in 276 patients before treatment and among 370 patients during or after treatment.

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marginal significanceP = 0.052so close (0.05 < p ≤ 0.1)

In multivariate analysis FT (P<0.001) and viral load (P = 0.007) were the most significant independent factors, with a marginal significance (P = 0.052) for ALT, and age (P = 0.03) ( Table 7 ).

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