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Antihypertensive medication prescription patterns and time trends for newly-diagnosed uncomplicated hypertension patients in Taiwan.

BMC Health Serv Res · 2008 · PMC2443138 · PMID 18559115

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a slightly increasing trendno p-value reported
The mono-therapy prescription rate for diuretics, at less than 10%, albeit with a slightly increasing trend with the passage of time (as shown in Figures 2 and 3 ), also implies that diuretics are currently considered in Taiwan to be only a second- or third-line medication; thus, there would appear to be considerable room for improvement, in terms of greater adherence to the existent clinical guidelines based on evidence as well as cost-effectiveness [ 16 , 18 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.