However, group comparisons by ELISA reveal a highly significant increase (approximately 13-fold) in mean TDP-43 absorbance levels in FTD compared to controls, whereas in AD the mean TDP-43 absorbance level was about 7-fold increased.
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TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration.
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