Perioperative use of statins in noncardiac surgery.

The findings of these studies are similar to the conclusion from the Statins for Risk Reduction in Surgery (StaRRS) study, a retrospective study with 1163 patients in which perioperative statin therapy was shown to have a highly significant myocardial protective effect in vascular patients, irrespective of their cholesterol levels ( O’Neil-Callahan et al 2005 ).

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There is an increasing trend towards endovascular surgery and this may involve the use of large amounts of contrast media with implications for renal function.

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