PPAR Ligands as Potential Modifiers of Breast Carcinoma Outcomes.

PPAR Res · 2008 · PMC2467456 · PMID 18645617

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marginally significantno p-value reported

Described associations between PPARG polymorphisms and breast carcinoma are also discrepant: some researchers see a marginally significant increase in the risk of breast cancer among women homozygous for the Ala allele of PPAR γ (Pro12Ala), causing a reduction in the transcriptional activity of PPAR γ 2 [ 35 ], while others stress that carriers of the same variant allele are at lower risk [ 36 ].

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