highly significantp=0.07
In the haplotype analysis, T-G was overrepresented in XFS subjects (p=7.7x10 −18 ), showing a highly significant difference in frequency between primary open-angle glaucoma (POAG) and the control group (p=0.07), but the G-G and G-A haplotypes were less represented in XFS subjects (p=1.1x10 −11 and p=1.0x10 −4 , respectively).