Lamin A/C is a risk biomarker in colorectal cancer.

PLoS One · 2008 · PMC2496895 · PMID 18714339

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highly significantno p-value reported

Unexpectedly, we found that expression of A-type lamins within a tumour was a highly significant risk indicator of tumour related mortality.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.