COMT val158met genotype affects recruitment of neural mechanisms supporting fluid intelligence.

In the scanner, a positive correlation was observed between COMT val allele load and performance (number of correct responses) for the spatial high g f task; r = 0.47, P < 0.03 2 tailed, with a nonsignificant trend in the same direction for the verbal high g f task; r = 0.31, P = 0.15 2 tailed.

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