Evidence of the role of tick subolesin in gene expression.

BMC Genomics · 2008 · PMC2518936 · PMID 18673577

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highly significantno p-value reported

[ 23 ] who showed that although maximum complementarity by itself is an unsatisfactory predictor of off-target RNAi effects, a highly significant association exists between off-targeting and exact complementarity between the seed region (bases 2–8) of siRNA and their off-targeted gene 3' untranslated region (UTR).

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