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Global self-organization of the cellular metabolic structure.

PLoS One · 2008 · PMC2519785 · PMID 18769681

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a decreasing trendno p-value reported
an increasing trendno p-value reported
The behavior of the time series tends to reverse itself, for instance, a decreasing trend in the past usually implies an increasing trend in the future and conversely, an increase in the past is likely to be followed by a decrease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.