Barely Significant
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The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides.

BMC Med Genet · 2008 · PMC2551592 · PMID 18789138

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hedged sentence
0.0000
closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 4 × 10 -8actually significant
The overall association between haplotypes and triglyceride levels was highly significant (p < 4 × 10 -8 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.