The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network.

Biochem J · 2008 · PMC2552392 · PMID 18522538

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highly significantno p-value reported

Thus in both HeLa and BS-C-1 cells, the effects of Exo2 on ERGIC and Golgi membranes are very similar to those of BFA, but with respect to the TGN, there is a highly significant difference: whereas BFA induces tubulation of the TGN [ 7 ], Exo2 does not.

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