Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.

Arthritis Res Ther · 2008 · PMC2575636 · PMID 18681962

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highly significantno p-value reported

CML is a tissue marker for accumulated oxidative stress [ 35 ]; therefore, its presence and that of its receptor RAGE are highly significant for both mechanisms underlying IVD degeneration and the likelihood that they could cause SIPS in human NP cells.

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