Barely Significant
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Effect of the assignment of ancestral CpG state on the estimation of nucleotide substitution rates in mammals.

BMC Evol Biol · 2008 · PMC2576242 · PMID 18826599

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highly significantP < 0.0001actually significant
The difference between substitution rates at non-CpG and non-CpG prone sites is highly significant both in introns and at fourfold sites (P < 0.0001; bootstrap test).

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