Furthermore, a fold-recognition bioinformatic analysis by the FFAS03 server revealed a highly significant score (−60.5 to −64.8) between BAS2713 or BAS4675 and the bicarbonate (CmpA) and nitrate (NrtA) substrate binding protein, suggesting a structural and functional homology despite the limited sequence conservation.
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The bicarbonate transporter is essential for Bacillus anthracis lethality.
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