Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon.

In contrast, blocking Unc5A/C receptor function had a highly significant effect on DTC outgrowth, inducing a significant shift of DTC axon outgrowth into the rostral Netrin-1–rich domain of the VTel ( Figure 9 G and 9 H) compared to control ( Figure 9 F– 9 H).

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