Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype.

Br J Cancer · 2008 · PMC2584952 · PMID 18841156

Europe PMC DOI

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0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

a statistical trendP =0.075so close (0.05 < p ≤ 0.1)

Overall, there were no statistical differences between PMR values in tumour tissue and clinicopathological factors (tumour size and stage, presence of axillary metastasis, histological grade, expression of ERs and HER2 or p53 status), with the exception of the expression of PR, for which a statistical trend toward higher methylation levels in PR-negative breast tumours was observed ( P =0.075; Mann–Whitney).

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