Search algorithms as a framework for the optimization of drug combinations.

PLoS Comput Biol · 2008 · PMC2590660 · PMID 19112483

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highly significantno p-value reported

In experiments identifying combinations of three doses of up to six drugs for selective killing of human cancer cells, search algorithms resulted in a highly significant enrichment of selective combinations compared with random searches.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.