Barely Significant
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Rationale for prostaglandin I2 in bone marrow oedema--from theory to application.

Arthritis Res Ther · 2008 · PMC2592809 · PMID 18834533

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highly significantno p-value reported
Iloprost showed a highly significant reduction in the level of pain evaluated by VAS during intravenous application within five days starting from 5.3 (sd = 2.0; range = 2 to 10) before treatment (day 0) to 2.5 (sd = 1.7; range = 0 to 6) on average at day five.

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