Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart.

Inhal Toxicol · 2009 · PMC2607137 · PMID 18925475

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fairly significantno p-value reported

(2006) noted that in RHMVE cells exposed to diesel exhaust particles, only secreted PAI-1, not total cellular PAI-1, levels decreased with decreasing mRNA ( Furuyama et al., 2006 ), we did see a fairly significant change in active PAI-1 levels in heart tissue extracts.

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