In a study comparing TLR4 expression levels in PBMC of asthma and healthy subjects before culture, and TLR4 expression levels show a highly significant association with asthma (manuscript in preparation).
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In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response.
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